A major earthquake has devestated Haiti, and in particular its capital Port-au-Prince.

craigslist recommends these charitable relief organizations, all of which have significant personnel and resources deployed in Haiti, and 4 out of 4 stars from Charity Navigator:

 

Also worth considering, the Albert Schweitzer Hospital, in Deschapelles, Haiti.

Google Missing Persons Finder
Google News feed for Haiti Earthquake
Haiti entry from Wikipedia
A divided island: the forces working against Haiti -  Jared Diamond, writing for UK Guardian

For comments or suggestions, there is a newly established earthquake forum.